Description

MOTS-c

MOTS-c is a 16-amino-acid mitochondria-derived peptide encoded within the mitochondrial 12S rRNA region. This innovative research peptide is studied for its influence on cellular energy sensing, glucose utilization, and metabolic stress-response pathways. It is an ideal candidate for investigating mitochondrial-to-nuclear signaling and cellular metabolic regulation.

RESEARCH

MOTS-c is provided as a research tool exclusively for in vitro laboratory studies. This peptide is designed for investigating molecular interactions and cellular pathways under controlled experimental conditions. Research focuses on AMPK-associated signaling, cellular glucose uptake, energy homeostasis, and responses to metabolic stress. Experimental findings do not establish therapeutic effects in humans. No claims are made regarding therapeutic effects.

CHEMICAL INFORMATION

• MOTS-c:
  • Molecular Formula: C101H152N28O22S2
  • Molecular Weight: 2174.62 g/mol
  • Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

RESEARCH APPLICATIONS

• Cellular Energy Metabolism: Investigate the influence of MOTS-c on cellular energy sensing, substrate utilization, and metabolic homeostasis.
• Glucose Metabolism: Study AMPK-associated signaling and glucose uptake pathways in controlled cellular models.
• Mitochondrial Signaling: Explore communication between mitochondrial status and nuclear stress-response gene expression.
• Metabolic Stress and Adaptation: Examine cellular responses to metabolic challenge, oxidative stress, and exercise-related signaling.

STORAGE AND HANDLING

• Store lyophilized powder at -20°C, subject to product-specific stability data.
• After reconstitution, follow a validated laboratory stability protocol and use promptly.
• Protect from direct sunlight and avoid repeated freeze-thaw cycles.
• Maintain aseptic techniques during laboratory handling to minimize contamination.

PRODUCT SPECIFICATION

• Purity: Verify against batch-specific Certificate of Analysis (COA)
• Appearance: Lyophilized powder (confirm against lot documentation)
• Solubility: Verify against manufacturer or batch-specific laboratory data

COMPLIANCE NOTICE

MOTS-c (10 mg) is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA and is not to be used for therapeutic, diagnostic, or clinical purposes. Any misuse of this product may violate applicable laws and regulations. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

BENEFITS BEING RESEARCHED

• AMPK-associated cellular energy sensing and metabolic regulation
• Glucose uptake and insulin-signaling pathways in experimental models
• Mitochondrial-to-nuclear signaling and metabolic stress responses
• Cellular adaptation to exercise-related and oxidative stress
• Lipid utilization and energy expenditure pathways in preclinical models
• Aging-associated metabolic signaling and cellular homeostasis

MECHANISM OF ACTION (Simplified)

• Mitochondrial Origin: MOTS-c is encoded within the mitochondrial 12S rRNA region and participates in mitochondria-associated cellular signaling.
• Energy Sensing: Experimental studies associate MOTS-c with folate-cycle changes, AICAR accumulation, and AMPK pathway activation.
• Glucose Regulation: Preclinical models link MOTS-c signaling with increased cellular glucose uptake and changes in glucose transporter expression.
• Stress Adaptation: Under certain stress conditions, MOTS-c has been observed to translocate to the nucleus and influence stress-response gene expression.
• Overall research focus = cellular metabolic flexibility, energy homeostasis, and adaptive signaling in experimental systems.

FORM / NOTES

Lyophilized vial containing 10 mg of MOTS-c for laboratory preparation.
Intended strictly for controlled laboratory research use.

LEGAL DISCLAIMER

This product is sold strictly for laboratory research use only.

By purchasing this product, the buyer represents and warrants that:

• The material will be used solely for in-vitro research purposes
• The buyer is qualified to handle laboratory reagents
• The product will not be used for human or animal consumption, injection, or application

Revyon Technologies assumes no liability for misuse or improper handling.

IMPORTANT NOTICE

Any use outside of stated research purposes is strictly prohibited.