Description

GHK-Cu

GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring tripeptide that forms a complex with copper ions to stimulate wound healing, collagen production, and cellular regeneration. It plays a central role in dermal repair, anti-aging, and antioxidant defense by activating genes involved in skin remodeling and reducing oxidative damage.

RESEARCH

GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper peptide that plays a critical role in tissue remodeling, wound healing, and cellular repair. It is composed of three amino acids (glycine, histidine, and lysine) bound to copper ions. GHK-Cu has been extensively studied for its potential to stimulate collagen production, regulate inflammation, and promote skin health and regeneration. GHK-Cu is provided in lyophilized powder form for research applications targeting cellular repair, skin health, and anti-inflammatory processes.

CHEMICAL INFORMATION

• Molecular Formula: C14H24N6O4Cu
• Molecular Weight: 340.84 g/mol*

* “GHK-Cu may appear as ~340 Da (peptide only) or ~404 Da (copper complex) depending on MS conditions. The blue color confirms copper is present in the complex.”

• Sequence: Gly-His-Lys

RESEARCH APPLICATIONS

• Promote Wound Healing: Investigate its ability to enhance tissue repair and regeneration.
• Support Skin Health: Study its role in collagen synthesis and improving skin elasticity and texture.
• Regulate Inflammation: Explore its anti-inflammatory properties in both acute and chronic conditions.
• Encourage Hair Growth: Examine its effects on stimulating hair follicles and reducing hair loss.

STORAGE AND HANDLING

• Store lyophilized powder at -20°C.
• Once reconstituted, store at 2-8°C and use promptly.
• Protect from direct sunlight and avoid repeated freeze-thaw cycles.
• Maintain aseptic techniques during handling to ensure sterility.

PRODUCT SPECIFICATION

• Purity: ≥99% (HPLC Certified)
• Appearance: Lyophilized white powder
• Solubility: Soluble in bacteriostatic water

COMPLIANCE NOTICE

GHK-Cu is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA and is not to be used for therapeutic, diagnostic, or clinical purposes. Any misuse of this product may violate applicable laws and regulations. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

BENEFITS BEING RESEARCHED

• Collagen, elastin, and glycosaminoglycan synthesis → improves skin firmness and elasticity
• Wound and scar healing by enhancing fibroblast and keratinocyte activity
• Inflammation and oxidative stress in skin and connective tissue
• Angiogenesis and microcirculation for improved nutrient delivery
• Regenerative genes associated with tissue remodeling and repair
• Skin tone, thickness, and overall youthfulness when used topically or systemically

MECHANISM OF ACTION (Simplified)

• Binds copper (II) ions → delivers bioavailable copper to cells for enzymatic activity
• Activates TGF-β and integrin pathways → stimulates fibroblast proliferation and ECM production
• Upregulates metalloproteinases (MMPs) for controlled tissue remodeling
• Down-regulates inflammatory cytokines (IL-6, TNF-α) → reduces inflammation and oxidative damage
• Increases VEGF and growth factor signaling → supports angiogenesis and repair

FORM / NOTES

Lyophilized vial for reconstitution (typically 5–10 mL bacteriostatic water).
Intended for research or compounded topical/injectable use depending on application.

LEGAL DISCLAIMER

This product is sold strictly for laboratory research use only.

By purchasing this product, the buyer represents and warrants that:

• The material will be used solely for in-vitro research purposes
• The buyer is qualified to handle laboratory reagents
• The product will not be used for human or animal consumption, injection, or application

Revyon Technologies assumes no liability for misuse or improper handling.

IMPORTANT NOTICE

Any use outside of stated research purposes is strictly prohibited.